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1

Metastatic Dermatofibrosarcoma Protuberans of the Vulva

Trevor M. Soergel, David L. Doering, Dennis O'Connor

Journal:

Gynecologic Oncology

Année:

1998

Langue:

english

Fichier:

PDF, 1.51 MB

english, 1998

2

APOLLO-1: a Randomized, Controlled, Phase 3 Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Pain Following Bunionectomy

Singla, Neil K., Senagore, Anthony, Viscusi, Eugene R., Burt, David A., Soergel, David

Journal:

The Spine Journal

Année:

2017

Langue:

english

Fichier:

PDF, 148 KB

english, 2017

3

Book reviews

Laura Miller, Michael Anesko, Beth Luey, Sandra L. Batalden, Philip M. Soergel, David H. Gilbert, Kenneth M. Avella, Richard C. Rowson, Ellen Altman, Retha M. Warnicke, Charles Johanningsmeier

Journal:

Publishing Research Quarterly

Année:

1994

Langue:

english

Fichier:

PDF, 2.28 MB

english, 1994

4

Effects of mastoparan and related peptides on phosphoinositide breakdown in HL-60 cells and cell-free preparations

Fabian Gusovsky, David G. Soergel, John W. Daly

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Année:

1991

Langue:

english

Fichier:

PDF, 519 KB

english, 1991

5

Editors' Note

Susil K. Sarna Ph.D., Nicholas W. Read M.D., Konrad H. Soergel M.D., David G. Grundy Ph.D.

Journal:

Neurogastroenterology & Motility

Année:

1989

Langue:

english

Fichier:

PDF, 109 KB

english, 1989

6

The effect of short chain fatty acids on transmural electrical potential across rat small intestine in vivo

Malcolm J. Wall, Richard J. Declusin, Konrad H. Soergel, R.David Baker

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1976

Langue:

english

Fichier:

PDF, 412 KB

english, 1976

7

TRV120027, a β-Arrestin Biased Ligand at the Angiotensin II Type 1 Receptor, Produces Unique Pharmacology and Is a Novel Potential Therapy for Heart Failure

Jonathan D. Violin, David G. Soergel, Scott M. DeWire, Dennis Yamashita, David Rominger, Erin J. Whalen, Maxine Gowen, Michael W. Lark

Journal:

Journal of Cardiac Failure

Année:

2010

Langue:

english

Fichier:

PDF, 57 KB

english, 2010

8

TRV120027, a Novel Beta-Arrestin Biased Ligand at the Angiotensin II Type I Receptor, Unloads the Heart and Maintains Renal Function When Added to Furosemide in Experimental Heart Failure

Guido Boerrigter, David G. Soergel, Michael W. Lark, John C. Burnett Jr.

Journal:

Journal of Cardiac Failure

Année:

2011

Langue:

english

Fichier:

PDF, 319 KB

english, 2011

9

First Human Dosing Experience With TRV027, a Novel Therapy for Acute Heart Failure

David G. Soergel, Ruth Ann Subach, Jonathan D. Violin, Dennis Yamashita, Maxine Gowen, Michael W. Lark

Journal:

Journal of Cardiac Failure

Année:

2012

Langue:

english

Fichier:

PDF, 89 KB

english, 2012

10

GPCR biased ligands as novel heart failure therapeutics

Violin, Jonathan D., Soergel, David G., Boerrigter, Guido, Burnett, John C., Lark, Michael W.

Journal:

Trends in Cardiovascular Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2013

11

Selection of primers for optimal taxonomic classification of environmental 16S rRNA gene sequences

Soergel, David A W, Dey, Neelendu, Knight, Rob, Brenner, Steven E

Journal:

The ISME Journal

Année:

2012

Langue:

english

Fichier:

PDF, 389 KB

english, 2012

12

TRVO27, A BETA-ARRESTIN BIASED LIGAND AT THE ANGIOTENSIN 2 TYPE 1 RECEPTOR, PRODUCES RAPID, REVERSIBLE CHANGES IN HEMODYNAMICS IN PATIENTS WITH STABLE SYSTOLIC HEART FAILURE

Soergel, David, Subach, Ruth Ann, James, Ian E., Cowan, Conrad L., Gowen, Maxine, Lark, Michael

Journal:

Journal of the American College of Cardiology

Année:

2013

Langue:

english

Fichier:

PDF, 153 KB

english, 2013

13

Biased ligands at G-protein-coupled receptors: promise and progress

Violin, Jonathan D., Crombie, Aimee L., Soergel, David G., Lark, Michael W.

Journal:

Trends in Pharmacological Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 727 KB

english, 2014

14

Association of gut microbiota with post-operative clinical course in Crohn’s disease

Neelendu Dey,David AW Soergel,Susanna Repo,Steven E Brenner

Journal:

BMC Gastroenterology

Année:

2013

Langue:

english

Fichier:

PDF, 869 KB

english, 2013

15

Biased agonism of the μ-opioid receptor by TRV130 increases analgesia and reduces on-target adverse effects versus morphine: A randomized, double-blind, placebo-controlled, crossover study in healthy volunteers

Soergel, David G., Subach, Ruth Ann, Burnham, Nancy, Lark, Michael W., James, Ian E., Sadler, Brian M., Skobieranda, Franck, Violin, Jonathan D., Webster, Lynn R.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 481 KB

english, 2014

16

Erratum: Biased ligands at G protein-coupled receptors: promise and progress

Violin, Jonathan D., Crombie, Aimee L., Soergel, David G., Lark, Michael W.

Journal:

Trends in Pharmacological Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 139 KB

english, 2014

17

First Clinical Experience with TRV027: Pharmacokinetics and Pharmacodynamics in Healthy Volunteers

Soergel, David G., Subach, Ruth Ann, Cowan, Conrad L., Violin, Jonathan D., Lark, Michael W.

Journal:

Journal of Clinical Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 603 KB

english, 2013

18

First Clinical Experience With TRV130: Pharmacokinetics and Pharmacodynamics in Healthy Volunteers

Soergel, David G., Ann Subach, Ruth, Sadler, Brian, Connell, John, Marion, Alan S., Cowan, Conrad L., Violin, Jonathan D., Lark, Michael W.

Journal:

Journal of Clinical Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 871 KB

english, 2014

19

Heart Failure Therapeutics on the Basis of a Biased Ligand of the Angiotensin-2 Type 1 Receptor

Felker, G. Michael, Butler, Javed, Collins, Sean P., Cotter, Gad, Davison, Beth A., Ezekowitz, Justin A., Filippatos, Gerasimos, Levy, Phillip D., Metra, Marco, Ponikowski, Piotr, Soergel, David G., T

Journal:

Journal of the American College of Cardiology: Heart Failure

Année:

2015

Langue:

english

Fichier:

PDF, 707 KB

english, 2015

20

[ACM Press the 27th annual international conference - Sheffield, United Kingdom (2004.07.25-2004.07.29)] Proceedings of the 27th annual international conference on Research and development in information retrieval - SIGIR '04 - Building an information retrieval test collection for spontaneous conversational speech

Oard, Douglas W., Mayfield, James, Kharevych, Liliya, Strassel, Stephanie, Soergel, Dagobert, Doermann, David, Huang, Xiaoli, Murray, G. Craig, Wang, Jianqiang, Ramabhadran, Bhuvana, Franz, Martin, Gu

Année:

2004

Langue:

english

Fichier:

PDF, 156 KB

english, 2004

21

SPIE Proceedings [SPIE 12th World Congress of the International Photodynamic Association - Seattle, WA (Thursday 11 June 2009)] Photodynamic Therapy: Back to the Future - Photodynamic therapy of cervical intraepithelial neoplasia using hexaminolevulinate and methylaminolevulinate

Soergel, Philipp, Staboulidou, Ismini, Hertel, Herrmann, Schippert, Cordula, Hillemanns, Peter, Kessel, David H.

Année:

2009

Langue:

english

Fichier:

PDF, 117 KB

english, 2009

22

The Immunotherapeutic Potential of Activated Canine Alveolar Macrophages and Antitumor Monoclonal Antibodies in Metastatic Canine Melanoma

Soergel, Steve A., MacEwen, E. Gregory, Vail, David M., Potter, David M., Sondel, Paul M., Helfand, Stuart C.

Journal:

Journla of Immunotherapy

Année:

1999

Fichier:

PDF, 1006 KB

1999

23

A randomized, phase 2 study investigating TRV130, a biased ligand of the μ-opioid receptor, for the intravenous treatment of acute pain

Viscusi, Eugene R., Webster, Lynn, Kuss, Michael, Daniels, Stephen, Bolognese, James A., Zuckerman, Seth, Soergel, David G., Subach, Ruth Ann, Cook, Emily, Skobieranda, Franck

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 720 KB

english, 2016

24

Dose Interruptions with Morphine vs Oliceridine (TRV130), a Novel μ Receptor G Protein Pathway Selective (μ-GPS) Modulator: Analysis from a Placebo- and Morphine-Controlled Phase 2b Study in Patients Following Abdominoplasty

Senagore, Anthony J., Soergel, David, Burt, David, Skobieranda, Franck, Singla, Neil

Journal:

Journal of the American College of Surgeons

Année:

2016

Langue:

english

Fichier:

PDF, 97 KB

english, 2016

25

I2. Rapid Onset of Pain Relief with Oliceridine (TRV130) vs. Morphine: a Phase 2a/b Study Analysis

Soergel, David, Viscusi, Eugene, Webster, Lynn, Burt, David, Skobieranda, Franck

Journal:

Pain Management Nursing

Année:

2017

Langue:

english

Fichier:

PDF, 43 KB

english, 2017

26

Treatment of spontaneous preterm labour with retosiban: a phase II pilot dose-ranging study

Thornton, Steven, Valenzuela, Guillermo, Baidoo, Charlotte, Fossler, Michael J., Montague, Timothy H., Clayton, Linda, Powell, Marcy, Snidow, Jerry, Stier, Brendt, Soergel, David

Journal:

British Journal of Clinical Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 456 KB

english, 2017

27

I1. A Randomized, Placebo- and Active-Controlled Phase 2b Study Investigating Oliceridine (TRV130)

Soergel, David, Minkowitz, Harold, Burt, David, Skobieranda, Franck

Journal:

Pain Management Nursing

Année:

2017

Langue:

english

Fichier:

PDF, 55 KB

english, 2017

28

Gastrointestinal Tolerability With Oliceridine, A Novel µ Receptor G Protein Pathway Selective (µ-GPS) Modulator [4H]

Steinberg, Adam C., Soergel, David, Burt, David, Skobieranda, Franck

Journal:

Obstetrics & Gynecology

Année:

2017

Langue:

english

Fichier:

PDF, 151 KB

english, 2017

29

Oliceridine, a Novel G Protein-Biased Ligand at the μ-Opioid Receptor, Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. II: Simulation of Potential Phase 3 Study Designs Using a Pharmacokinetic/Pharmacodynamic Model

Fossler, Michael J., Sadler, Brian M., Farrell, Colm, Burt, David A., Pitsiu, Maria, Skobieranda, Franck, Soergel, David G.

Journal:

Journal of Clinical Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 971 KB

english, 2018

30

Oliceridine (TRV130), a Novel G Protein-Biased Ligand at the μ-Opioid Receptor, Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. I: Development of a Pharmacokinetic/Pharmacodynamic Model

Fossler, Michael J., Sadler, Brian M., Farrell, Colm, Burt, David A., Pitsiu, Maria, Skobieranda, Franck, Soergel, David G.

Journal:

Journal of Clinical Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 940 KB

english, 2018

31

A randomized, Phase IIb study investigating oliceridine (TRV130), a novel µ-receptor G-protein pathway selective (µ-GPS) modulator, for the management of moderate to severe acute pain following abdominoplasty

Singla, Neil, Minkowitz, Harold, Soergel, David, Burt, David, Subach, Ruth Ann, Salamea, Monica, Fossler, Michael, Skobieranda, Franck

Journal:

Journal of Pain Research

Année:

2017

Langue:

english

Fichier:

PDF, 393 KB

english, 2017

32

Rampant software errors may undermine scientific results

Soergel, David A. W.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 823 KB

english, 2015

33

Maintained contractile reserve in a transgenic mouse model of myocardial stunning

Kögler, Harald, Soergel, David G., Murphy, Anne M., Marbán, Eduardo

Journal:

American journal of physiology. Heart and circulatory physiology

Année:

2001

Langue:

english

Fichier:

PDF, 222 KB

english, 2001

34

APOLLO-1: a randomized placebo and active-controlled phase III study investigating oliceridine (TRV130), a G protein-biased ligand at the µ-opioid receptor, for management of moderate-to-severe acute pain following bunionectomy

Viscusi, Eugene R, Skobieranda, Franck, Soergel, David G, Cook, Emily, Burt, David A, Singla, Neil

Journal:

Journal of Pain Research

Année:

2019

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2019

35

APOLLO ‐2: A Randomized, Placebo and Active‐Controlled Phase III Study Investigating Oliceridine ( TRV 130), a G Protein‐Biased Ligand at the μ‐Opioid Receptor, for Management of Moderate to Severe Acute Pain Following Abdominoplasty

Singla, Neil K., Skobieranda, Franck, Soergel, David G., Salamea, Monica, Burt, David A., Demitrack, Mark A., Viscusi, Eugene R.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2019

36

A First‐in‐Human Clinical Study With TRV734, an Orally Bioavailable G‐Protein–Biased Ligand at the μ‐Opioid Receptor

James, Ian E., Skobieranda, Franck, Soergel, David G., Ramos, Kimberly A., Ruff, Dennis, Fossler, Michael J.

Journal:

Clinical Pharmacology in Drug Development

Année:

2019

Langue:

english

Fichier:

PDF, 815 KB

english, 2019

37

Gastric Emptying in Patients With Diabetes Mellitus

Loo, Franklin D., Palmer, David W., Soergel, Konrad H., Kalbfleisch, John H., Wood, Carol M.

Journal:

Gastroenterology

Année:

1984

Fichier:

PDF, 1.07 MB

1984